Luxembourg and the Greater Region provide a unique and excellent laboratory for investigating social policy issues that are of key importance for the process of European integration. Substantial institutional differentials within a relatively small distance and their impact on cross-border activities like firm location, household mobility, monetary flows, and the like are generating an abundance of research topics, which are of relevance for a better understanding of the mechanisms of economic and social convergence or divergence.

The research activities are organised among three research departments and a transversal coordination unit. Their mission consists of producing relevant insights for social and economic policy based on empirical evidence. The department "Labor Market" is primarily addressing the process of labor income determination, both from the worker's perspective as well as from the perspective of companies and employers. The department "Living Conditions" is focussing on the social aspects of income and wealth distribution. The spatial dimension of social and economic policy is subject of the research agenda of the department "Urban Development and Mobility".

The transversal coordination unit is in charge of providing common service across departments and to ensure the mobilization of synergies coming from the interdisciplinarity of the institute. Common service includes survey collection and data generation, data provision, and seminar activities. Mobilizing synergies based on interdisciplinarity is based on initiating research activities across departments and disciplines, including workshops, edited volumes, and research projects.